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Found 3 Enz. Inhib. hit(s) with Target = 'Purine nucleoside phosphorylase' and Ligand = 'BDBM50247149'
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Universit£

Curated by ChEMBL
LigandPNGBDBM50247149(5'-Methylthio-ImmH | CHEMBL473929 | US9290501, (A))
Affinity DataKi:  2.70nMAssay Description:Inhibition of Plasmodium falciparum 3D7 PNP expressed in Escherichia coli assessed as reduction in uric acid formation by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Albert Einstein College Of Medicine Of Yeshiva University

Curated by ChEMBL
LigandPNGBDBM50247149(5'-Methylthio-ImmH | CHEMBL473929 | US9290501, (A))
Affinity DataKi:  101nMAssay Description:Initial binding affinity to wild type human PNPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Albert Einstein College Of Medicine Of Yeshiva University

Curated by ChEMBL
LigandPNGBDBM50247149(5'-Methylthio-ImmH | CHEMBL473929 | US9290501, (A))
Affinity DataKi:  303nMAssay Description:Inhibition of human PNP expressed in Escherichia coli assessed as reduction in uric acid formation by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed