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Found 2 Enz. Inhib. hit(s) with Target = 'RAF proto-oncogene serine/threonine-protein kinase' and Ligand = 'BDBM514773'
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Kinnate Biopharma

US Patent
LigandPNGBDBM514773((3S)-N-(3-{2-[(3R,4R)-3-amino-4-hydroxypyrrolidin-...)
Affinity DataIC50: <10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Kinnate Biopharma

US Patent
LigandPNGBDBM514773((3S)-N-(3-{2-[(3R,4R)-3-amino-4-hydroxypyrrolidin-...)
Affinity DataIC50: <10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent