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Found 3 Enz. Inhib. hit(s) with Target = 'RNA-directed RNA polymerase' and Ligand = 'BDBM50491701'
TargetRNA-directed RNA polymerase(Hepacivirus C)
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50491701(CHEMBL2387643)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of HCV NS5B polymerase P495L mutant assessed as inhibition of radioactive UMP incorporation into nascent RNA using poly aA/U12 template-pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepacivirus C)
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50491701(CHEMBL2387643)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of HCV NS5B polymerase M423T mutant assessed as inhibition of radioactive UMP incorporation into nascent RNA using poly aA/U12 template-pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepacivirus C)
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50491701(CHEMBL2387643)
Affinity DataIC50:  4.78E+4nMAssay Description:Inhibition of HCV NS5B polymerase M414T mutant assessed as inhibition of radioactive UMP incorporation into nascent RNA using poly aA/U12 template-pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed