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Found 4 Enz. Inhib. hit(s) with Target = 'RNA-directed RNA polymerase' and Ligand = 'BDBM50507437'
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50507437(CHEMBL4549638)
Affinity DataEC50:  5.40nMAssay Description:Inhibition of HCV genotype 2a JFH1 NS5B RNA dependent RNA polymerase infected in human HuH7 replicon cells after 3 days by luciferase reporter gene a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50507437(CHEMBL4549638)
Affinity DataEC50:  44nMAssay Description:Inhibition of HCV genotype 1b NS5B RNA dependent RNA polymerase C316N mutant infected in human HuH7 replicon cells after 3 days by luciferase reporte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50507437(CHEMBL4549638)
Affinity DataEC50:  7.70nMAssay Description:Inhibition of HCV genotype 1a NS5B RNA dependent RNA polymerase infected in human HuH7 replicon cells after 3 days by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50507437(CHEMBL4549638)
Affinity DataEC50:  8.80nMAssay Description:Inhibition of HCV genotype 1b NS5B RNA dependent RNA polymerase infected in human HuH7 replicon cells after 3 days by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed