Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with Target = 'RNA-directed RNA polymerase' and Ligand = 'BDBM50536235'
TargetRNA-directed RNA polymerase(Hepacivirus C)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50536235BDBM50536235(Lomibuvir | VX-222)
Affinity DataEC50:  30nMAssay Description:Inhibition of HCV genotype 1a NS5B M423I mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepacivirus C)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50536235BDBM50536235(Lomibuvir | VX-222)
Affinity DataEC50:  65nMAssay Description:Inhibition of HCV genotype 1a NS5B M423V mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepacivirus C)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50536235BDBM50536235(Lomibuvir | VX-222)
Affinity DataEC50:  310nMAssay Description:Inhibition of HCV genotype 1a NS5B M423T mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepacivirus C)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50536235BDBM50536235(Lomibuvir | VX-222)
Affinity DataEC50:  320nMAssay Description:Inhibition of HCV genotype 1a NS5B L419I mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepacivirus C)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50536235BDBM50536235(Lomibuvir | VX-222)
Affinity DataEC50:  320nMAssay Description:Inhibition of HCV genotype 1a NS5B L419M mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed