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Found 2 Enz. Inhib. hit(s) with Target = 'Receptor-type tyrosine-protein kinase FLT3' and Ligand = 'BDBM389573'
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Vichem Chemie Research

Curated by ChEMBL
LigandPNGBDBM389573(N'-{6-bromo-2-[(E)-2-(3,4- difluorophenyl)vinyl]qu...)
Affinity DataIC50:  740nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin) using TAMRA-Src-tide as substrate measured after 1 hr in presence of ATP at its Km concentration by IM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Vichem Chemie Research

Curated by ChEMBL
LigandPNGBDBM389573(N'-{6-bromo-2-[(E)-2-(3,4- difluorophenyl)vinyl]qu...)
Affinity DataIC50:  2.00E+3nMAssay Description:FLT3(ITD) biochemical assays were performed on two different assay system platforms, using TranscreenerŽ ADP Assay FP method (BellBrook Labs, Madison...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent