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Found 5 Enz. Inhib. hit(s) with Target = 'Renin' and Ligand = 'BDBM50273160'
TargetRenin(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50273160(IMARIKIREN)
Affinity DataIC50:  0.430nMAssay Description:Inhibition of recombinant human renin using angiotensinogen as substrate pretreated for 10 mins followed by substrate addition measured after 30 mins...More data for this Ligand-Target Pair
TargetRenin(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50273160(IMARIKIREN)
Affinity DataIC50:  0.840nMAssay Description:Inhibition of recombinant human renin using angiotensinogen as substrate pretreated for 10 mins followed by substrate addition measured after 30 mins...More data for this Ligand-Target Pair
TargetRenin(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50273160(IMARIKIREN)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of renin in human plasma by radioimmunoassayMore data for this Ligand-Target Pair
TargetRenin(Macaca mulatta)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50273160(IMARIKIREN)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of renin in monkey plasmaMore data for this Ligand-Target Pair
TargetRenin(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50273160(IMARIKIREN)
Affinity DataIC50:  310nMAssay Description:Inhibition of renin in rat plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed