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Found 2 Enz. Inhib. hit(s) with Target = 'Replicase polyprotein 1ab' and Ligand = 'BDBM11245'
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Taiwan University

LigandPNGBDBM11245(AG7088 analogue 1c | CHEMBL194398 | ethyl (2E,4S)-...)
Affinity DataIC50: >1.00E+5nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Taiwan University

LigandPNGBDBM11245(AG7088 analogue 1c | CHEMBL194398 | ethyl (2E,4S)-...)
Affinity DataIC50:  8.70E+5nMAssay Description:Inhibition of SARS-CoV 3C-like protease by FRET based microplate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed