Compile Data Set for Download or QSAR
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Found 3 Enz. Inhib. hit(s) with Target = 'Replicase polyprotein 1ab' and Ligand = 'BDBM423435'
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Experimental Drug Development Centre

LigandPNGBDBM423435(WO2005113580-Ex-37 | cmdc.202100576, 24e)
Affinity DataIC50:  162nMAssay Description:Please point to the patents.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Experimental Drug Development Centre

LigandPNGBDBM423435(WO2005113580-Ex-37 | cmdc.202100576, 24e)
Affinity DataIC50:  180nMAssay Description:The SARS 3CLpro FRET assay measures the protease catalyzed cleavage of TAMRA- SITSAVLQSGFRKMK-(DABCYL)-OH to TAMRA - SITSAVLQ and SGFRKMK- (DABCYL)-O...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Experimental Drug Development Centre

LigandPNGBDBM423435(WO2005113580-Ex-37 | cmdc.202100576, 24e)
Affinity DataEC50:  9.30E+3nMAssay Description:Protection from SARS Infection: Neutral Red Endpoint The ability of compounds to protect cells against infection by the SARS coronavirus is measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed