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Found 9 Enz. Inhib. hit(s) with Target = 'Reverse transcriptase/RNaseH' and Ligand = 'BDBM50004152'
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50004152((HEPT) 1-(2-Hydroxy-ethoxymethyl)-5-methyl-6-pheny...)
Affinity DataIC50:  5.06E+3nMAssay Description:Concentration required to protect the cell against HIV-1 strain IIIB viral cytopathogenicity by 50% in MT-4 cellsMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50004152((HEPT) 1-(2-Hydroxy-ethoxymethyl)-5-methyl-6-pheny...)
Affinity DataIC50: >6.00E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase(RT)More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50004152((HEPT) 1-(2-Hydroxy-ethoxymethyl)-5-methyl-6-pheny...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibitory activity of the compound against HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50004152((HEPT) 1-(2-Hydroxy-ethoxymethyl)-5-methyl-6-pheny...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibitory concentration required to inhibit the HIV-1 reverse transcriptase activityMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50004152((HEPT) 1-(2-Hydroxy-ethoxymethyl)-5-methyl-6-pheny...)
Affinity DataIC50:  1.75E+4nMAssay Description:Inhibition of HIV-1 reverse transcriptase from peripheral blood mononuclear cells.More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50004152((HEPT) 1-(2-Hydroxy-ethoxymethyl)-5-methyl-6-pheny...)
Affinity DataIC50:  1.50E+5nMAssay Description:Inhibitory effect of the compound on HIV-1 reverse transcriptase activity using poly(rC)-oligo(dG) template primerMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50004152((HEPT) 1-(2-Hydroxy-ethoxymethyl)-5-methyl-6-pheny...)
Affinity DataIC50: >4.05E+5nMAssay Description:Inhibitory concentration against SO561945 (HIV 1 mutant RT) viral viral infection of MT-4 cellsMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50004152((HEPT) 1-(2-Hydroxy-ethoxymethyl)-5-methyl-6-pheny...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibitory effect of the compound on HIV-1 reverse transcriptase activity using poly(rA)-oligo(dT) template primerMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50004152((HEPT) 1-(2-Hydroxy-ethoxymethyl)-5-methyl-6-pheny...)
Affinity DataEC50:  7.00E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase at 37 degree centigradeMore data for this Ligand-Target Pair