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Found 5 Enz. Inhib. hit(s) with Target = 'Reverse transcriptase' and Ligand = 'BDBM50033863'
TargetReverse transcriptase(Human immunodeficiency virus 1)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50033863(CHEMBL3358176)
Affinity DataIC50:  3nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase L100I mutant assessed as reduction in enzyme activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50033863(CHEMBL3358176)
Affinity DataIC50:  18nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase assessed as reduction in enzyme activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50033863(CHEMBL3358176)
Affinity DataIC50:  26nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase V106A mutant assessed as reduction in enzyme activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50033863(CHEMBL3358176)
Affinity DataIC50:  50nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase K103N mutant assessed as reduction in enzyme activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50033863(CHEMBL3358176)
Affinity DataIC50:  2.23E+3nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase Y181I/Y181C mutant assessed as reduction in enzyme activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed