Found 3 Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 1' and Ligand = 'BDBM50515430' TargetRho-associated protein kinase 1(Homo sapiens (Human))
Hefei University Of Technology
Curated by ChEMBL
Hefei University Of Technology
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Inhibition of ROCK1 (unknown origin)More data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Hefei University Of Technology
Curated by ChEMBL
Hefei University Of Technology
Curated by ChEMBL
Affinity DataIC50: 5.5nMAssay Description:Table 2: Inhibitory effect of each compound synthesized above on Rho-associated protein kinase (ROCK) was tested.Method 1. 10 mM test compound was di...More data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Hefei University Of Technology
Curated by ChEMBL
Hefei University Of Technology
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibition of human ROCK1 using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 20 mins in presence of [gamma33P]ATP by filter binding me...More data for this Ligand-Target Pair
