Compile Data Set for Download or QSAR
maximum 50k data
Found 5 Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2' and Ligand = 'BDBM50044004'
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50044004(CHEMBL3356433)
Affinity DataIC50:  10nMAssay Description:Inhibition of LIMK2 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50044004(CHEMBL3356433)
Affinity DataIC50:  32nMAssay Description:Inhibition of human Rock2 assessed as incorporation of P33 from ATP into biotinylated-cofilin substrate by scintillation counting analysis in presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50044004(CHEMBL3356433)
Affinity DataIC50:  340nMAssay Description:Inhibition of human Rock2 assessed as incorporation of P33 from ATP into biotinylated-cofilin substrate by scintillation counting analysis in presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50044004(CHEMBL3356433)
Affinity DataIC50:  340nMAssay Description:Inhibition of ROCK2 (unknown origin) by Kinase Glo luminescence assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50044004(CHEMBL3356433)
Affinity DataKd: <1.00E+3nMAssay Description:Binding affinity to human Rock2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed