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Found 9 Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2' and Ligand = 'BDBM50087135'
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Hefei University Of Technology

Curated by ChEMBL
LigandPNGBDBM50087135(CHEMBL3426621)
Affinity DataKi:  330nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Hefei University Of Technology

Curated by ChEMBL
LigandPNGBDBM50087135(CHEMBL3426621)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Hefei University Of Technology

Curated by ChEMBL
LigandPNGBDBM50087135(CHEMBL3426621)
Affinity DataIC50:  19nMAssay Description:Inhibition of Rock2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Hefei University Of Technology

Curated by ChEMBL
LigandPNGBDBM50087135(CHEMBL3426621)
Affinity DataIC50:  19nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Hefei University Of Technology

Curated by ChEMBL
LigandPNGBDBM50087135(CHEMBL3426621)
Affinity DataIC50:  19nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Hefei University Of Technology

Curated by ChEMBL
LigandPNGBDBM50087135(CHEMBL3426621)
Affinity DataIC50:  19nMAssay Description:Inhibition of N-terminal GST-fused human ROCK2 catalytic domain ( 1 to 553 residues) expressed in baculovirus expression system using Long S6 Kinase ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Hefei University Of Technology

Curated by ChEMBL
LigandPNGBDBM50087135(CHEMBL3426621)
Affinity DataIC50:  19nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Hefei University Of Technology

Curated by ChEMBL
LigandPNGBDBM50087135(CHEMBL3426621)
Affinity DataIC50:  21nMAssay Description:Inhibition of ROCK2 (unknown origin) using biotin as substrate incubated for 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Hefei University Of Technology

Curated by ChEMBL
LigandPNGBDBM50087135(CHEMBL3426621)
Affinity DataIC50:  197nMAssay Description:Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed