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Found 2 Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2 [1-552]' and Ligand = 'BDBM578415'
TargetRho-associated protein kinase 2 [1-552](Homo sapiens (Human))
Kadmon

US Patent
LigandPNGBDBM578415(N-(4-(1H-pyrazol-4-yl)phenyl)-2-(ethylamino)-2-(p-...)
Affinity DataIC50:  3.10nMAssay Description:Compounds activities were measured by Z'-lyte kinase kit (ThermoFisher Scientific). The percent inhibition rate was calculated by normalizing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2 [1-552](Homo sapiens (Human))
Kadmon

US Patent
LigandPNGBDBM578415(N-(4-(1H-pyrazol-4-yl)phenyl)-2-(ethylamino)-2-(p-...)
Affinity DataIC50:  4nMAssay Description:Compounds activities were measured by Z'-lyte kinase kit (ThermoFisher Scientific). The percent inhibition rate was calculated by normalizing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent