Found 4 Enz. Inhib. hit(s) with Target = 'Ribonucleoside-diphosphate reductase large subunit' and Ligand = 'BDBM50247408' TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Case Western Reserve University
Curated by ChEMBL
Case Western Reserve University
Curated by ChEMBL
Affinity DataKi: 5.00E+3nMAssay Description:Competitive inhibition of human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL using [14C]-ADP as substrateMore data for this Ligand-Target Pair
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Case Western Reserve University
Curated by ChEMBL
Case Western Reserve University
Curated by ChEMBL
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL using [14C]-ADP as substrate after 3 mins by liquid scintillation cou...More data for this Ligand-Target Pair
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Case Western Reserve University
Curated by ChEMBL
Case Western Reserve University
Curated by ChEMBL
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL using [14C]-ADP as substrate by boronate affinity chromatographyMore data for this Ligand-Target Pair
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Case Western Reserve University
Curated by ChEMBL
Case Western Reserve University
Curated by ChEMBL
Affinity DataKd: 3.70E+4nMAssay Description:Binding affinity to human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL by fluorescence spectrophotometric methodMore data for this Ligand-Target Pair
