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Found 5 Enz. Inhib. hit(s) with Target = 'Ribosomal protein S6 kinase alpha-6' and Ligand = 'BDBM25017'
TargetRibosomal protein S6 kinase alpha-6(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL
LigandPNGBDBM25017(2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimeth...)
Affinity DataIC50:  12nMAssay Description:Inhibition of RSK4 (unknown origin) incubated for 40 mins in presence of ATP and lipid substrate by Kinase-Glo plus luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-6(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL
LigandPNGBDBM25017(2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimeth...)
Affinity DataIC50:  15nMAssay Description:Inhibition of RSK4 (unknown origin) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK a substrate by [32P] gammaATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-6(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL
LigandPNGBDBM25017(2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimeth...)
Affinity DataIC50:  15nMAssay Description:Inhibition of RSK4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetRibosomal protein S6 kinase alpha-6(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL
LigandPNGBDBM25017(2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimeth...)
Affinity DataIC50:  15nMpH: 7.5 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-6(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL
LigandPNGBDBM25017(2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimeth...)
Affinity DataIC50:  15nMAssay Description:Inhibition of RSK4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed