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Found 3 Enz. Inhib. hit(s) with Target = 'Ribosomal protein S6 kinase beta-1' and Ligand = 'BDBM369719'
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM369719(US10233160, Compound 9 | US9981925, Compound 9)
Affinity DataIC50:  501nMAssay Description:Inhibition of N-terminal 6His-tagged human recombinant p70S6K T412E mutant (1 to 421 residues) in Sf21 insect cells using FITC-AHA-AKRRRLSSLRA-OH sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM369719(US10233160, Compound 9 | US9981925, Compound 9)
Affinity DataIC50:  750nMAssay Description:p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM369719(US10233160, Compound 9 | US9981925, Compound 9)
Affinity DataIC50:  750nMAssay Description:p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent