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Found 3 Enz. Inhib. hit(s) with Target = 'Ribosomal protein S6 kinase beta-1' and Ligand = 'BDBM50379531'
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50379531(CHEMBL2012702)
Affinity DataIC50:  2nMAssay Description:Inhibition of p70S6K after 3 hrs by luciferase based chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50379531(CHEMBL2012702)
Affinity DataIC50:  43nMAssay Description:Inhibition of p70S6K-mediated ribosomal protein S6 phosphorylation in human A549 cells after 3 hrs by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50379531(CHEMBL2012702)
Affinity DataIC50:  141nMAssay Description:Inhibition of p70S6K-mediated ribosomal protein S6 phosphorylation in human PC3 cells after 3 hrs by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed