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Found 4 Enz. Inhib. hit(s) with Target = 'Ryanodine receptor 1' and Ligand = 'BDBM50044994'
TargetRyanodine receptor 1(Oryctolagus cuniculus)
University Of California

Curated by ChEMBL
LigandPNGBDBM50044994(2,6,9,11,13,14-hexahydroxy-11-isopropyl-3,7,10-tri...)
Affinity DataIC50:  2nMAssay Description:Displacement of [3H]ryanodine from Ca2+-ryanodine receptor in Oryctolagus cuniculus (rabbit) skeletal muscle sarcoplasmic reticulum after 2 hr by com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRyanodine receptor 1(Oryctolagus cuniculus)
University Of California

Curated by ChEMBL
LigandPNGBDBM50044994(2,6,9,11,13,14-hexahydroxy-11-isopropyl-3,7,10-tri...)
Affinity DataIC50:  3.5nMAssay Description:Displacement of [3H]ryanodine from Ca2+-ryanodine receptor in Oryctolagus cuniculus (rabbit) skeletal muscle sarcoplasmic reticulum after 1 hr by com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRyanodine receptor 1(Oryctolagus cuniculus)
University Of California

Curated by ChEMBL
LigandPNGBDBM50044994(2,6,9,11,13,14-hexahydroxy-11-isopropyl-3,7,10-tri...)
Affinity DataIC50:  6.20nMAssay Description:Affinity for sarcoplasmic reticular calcium release channel (SR CRC) of rabbit skeletal membrane vesiclesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRyanodine receptor 1(Oryctolagus cuniculus)
University Of California

Curated by ChEMBL
LigandPNGBDBM50044994(2,6,9,11,13,14-hexahydroxy-11-isopropyl-3,7,10-tri...)
Affinity DataIC50:  10nMAssay Description:Displacement of [3H]ryanodine from Ca2+-ryanodine receptor in Oryctolagus cuniculus (rabbit) skeletal muscle sarcoplasmic reticulum after 80 min by c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed