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Found 2 Enz. Inhib. hit(s) with Target = 'S-adenosylmethionine synthase isoform type-2' and Ligand = 'BDBM50070638'
TargetS-adenosylmethionine synthase isoform type-2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50070638(1-AMINOCYCLOPENTANECARBOXYLIC ACID | 1-Amino-cyclo...)
Affinity DataIC50:  1.30E+6nMAssay Description:Inhibition of MAT2A in human Huh-7 cells assessed as inhibition of S-adenosyl methionine production measured after 6 hrs by Rapid Fire Mass Spectrome...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50070638(1-AMINOCYCLOPENTANECARBOXYLIC ACID | 1-Amino-cyclo...)
Affinity DataIC50:  5.60E+6nMAssay Description:Inhibition of MAT2A in human NCI-H520 cells transfected with MAT2A empty vector assessed as inhibition of S-adenosyl methionine production measured a...More data for this Ligand-Target Pair
In DepthDetails PubMed