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Found 3 Enz. Inhib. hit(s) with Target = 'Sepiapterin reductase' and Ligand = 'BDBM187258'
TargetSepiapterin reductase(Homo sapiens (Human))
Solace Pharmaceuticals

US Patent
LigandPNGBDBM187258(US9169234, 23)
Affinity DataIC50:  11nMpH: 6.5 T: 2°CAssay Description:To screen for SPR inhibition, a biochemical assay based on LC/MS (and chromogenic) read-out has been developed. The LC/MS assay monitors the produc...More data for this Ligand-Target Pair
TargetSepiapterin reductase(Homo sapiens (Human))
Solace Pharmaceuticals

US Patent
LigandPNGBDBM187258(US9169234, 23)
Affinity DataIC50:  12nMpH: 6.5 T: 2°CAssay Description:To screen for SPR inhibition, a biochemical assay based on LC/MS (and chromogenic) read-out has been developed. The LC/MS assay monitors the product ...More data for this Ligand-Target Pair
TargetSepiapterin reductase(Homo sapiens (Human))
Solace Pharmaceuticals

US Patent
LigandPNGBDBM187258(US9169234, 23)
Affinity DataIC50:  310nMAssay Description:Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysisMore data for this Ligand-Target Pair