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Found 4 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase B-raf' and Ligand = 'BDBM50289149'
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Korea Institute of Science and Technology

US Patent
LigandPNGBDBM50289149(GW305074X | GW5074 | US10570155, GW5074 | US113324...)
Affinity DataIC50:  8.52nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Korea Institute of Science and Technology

US Patent
LigandPNGBDBM50289149(GW305074X | GW5074 | US10570155, GW5074 | US113324...)
Affinity DataIC50:  8.52nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Korea Institute of Science and Technology

US Patent
LigandPNGBDBM50289149(GW305074X | GW5074 | US10570155, GW5074 | US113324...)
Affinity DataIC50:  30nMAssay Description:Inhibition of BRAF (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Korea Institute of Science and Technology

US Patent
LigandPNGBDBM50289149(GW305074X | GW5074 | US10570155, GW5074 | US113324...)
Affinity DataIC50:  71nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed