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Found 4 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase PAK 1' and Ligand = 'BDBM50201641'
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50201641(CHEMBL3923175)
Affinity DataIC50:  0.330nMAssay Description:Inhibition of PAK1 (unknown origin) by ATP-kinaseGlo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50201641(CHEMBL3923175)
Affinity DataIC50: <1nMAssay Description:Inhibition of N-terminal FLAG-tagged recombinant human PAK1 (150-end residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50201641(CHEMBL3923175)
Affinity DataIC50:  59nMAssay Description:Inhibition of PAK1 phosphorylation in human MCF10A cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50201641(CHEMBL3923175)
Affinity DataKd:  0.280nMAssay Description:Binding affinity to human PAK1 (S149 to H545 residues) expressed in bacterial expression system by KINOMEscan assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed