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Found 2 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase TBK1' and Ligand = 'BDBM357872'
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
The Regents of The University of Michigan

US Patent
LigandPNGBDBM357872(US10214536, Compound 42)
Affinity DataIC50:  190nMAssay Description:Kinase assays are commonly used for determining the ability of a small molecule to inhibit enzyme activity. By measuring the degree of phosphorylatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
The Regents of The University of Michigan

US Patent
LigandPNGBDBM357872(US10214536, Compound 42)
Affinity DataIC50:  750nMAssay Description:Inhibition of human TBK1 (1 to 657 residues) expressed in Baculovirus infected SF9 insect cells using myelin basic protein as substrate in presence o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed