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Found 2 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase TBK1' and Ligand = 'BDBM485830'
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM485830(US10946017, Compound 27)
Affinity DataIC50:  48nMMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM485830(US10946017, Compound 27)
Affinity DataKd:  130nMAssay Description:In vitro degradation assay protocol for compounds 3-33: Panc02.13 cells were purchased from ATCC and cultured in RPMI-1640 (Gibco), supplemented with...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent