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Found 2 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase TBK1' and Ligand = 'BDBM485844'
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM485844(US10946017, Compound 11DC50:)
Affinity DataIC50:  12nMMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM485844(US10946017, Compound 11DC50:)
Affinity DataKd:  4.60nMAssay Description:In vitro degradation assay protocol for compounds 3-33: Panc02.13 cells were purchased from ATCC and cultured in RPMI-1640 (Gibco), supplemented with...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent