Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-2' and Ligand = 'BDBM248940'
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM248940(US9434725, 171 | US9434725, 182 | US9434725, 183)
Affinity DataKi:  0.109nM ΔG°:  -56.9kJ/molepH: 7.2 T: 2°CAssay Description:PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J. F., a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM248940(US9434725, 171 | US9434725, 182 | US9434725, 183)
Affinity DataKi:  0.204nM ΔG°:  -55.3kJ/molepH: 7.2 T: 2°CAssay Description:PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J. F., a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM248940(US9434725, 171 | US9434725, 182 | US9434725, 183)
Affinity DataKi:  0.761nM ΔG°:  -52.0kJ/molepH: 7.2 T: 2°CAssay Description:PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J. F., a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent