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Found 3 Enz. Inhib. hit(s) with Target = 'Serine protease hepsin' and Ligand = 'BDBM50272187'
TargetSerine protease hepsin(Homo sapiens (Human))
University Of Helsinki

Curated by ChEMBL
LigandPNGBDBM50272187(CHEMBL4128554)
Affinity DataIC50:  90nMAssay Description:Inhibition of recombinant C-terminal His10-tagged human Hepsin (R45 to L17 residues) D161E/ R162K double mutant expressed in mouse NS0 cells using Bo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease hepsin(Homo sapiens (Human))
University Of Helsinki

Curated by ChEMBL
LigandPNGBDBM50272187(CHEMBL4128554)
Affinity DataIC50:  190nMAssay Description:Inhibition of recombinant C-terminal His10-tagged human Hepsin (R45 to L17 residues) D161E/ R162K double mutant expressed in mouse NS0 cells using Bo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease hepsin(Homo sapiens (Human))
University Of Helsinki

Curated by ChEMBL
LigandPNGBDBM50272187(CHEMBL4128554)
Affinity DataIC50:  1.29E+3nMAssay Description:Inhibition of doxycycline induced Hepsin in human MCF10A cells using Boc-QRR-AMC as substrate preincubated for 24 hrs followed by doxycycline inducti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed