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Found 3 Enz. Inhib. hit(s) with Target = 'Shiga toxin subunit A' and Ligand = 'BDBM50199482'
TargetShiga toxin subunit A(Shigella dysenteriae)
TBA

Curated by ChEMBL
LigandPNGBDBM50199482(CHEMBL3963596)
Affinity DataKi:  4.25E+4nMAssay Description:Inhibition of Shigella dysenteriae type 1 Shiga toxin A subunit assessed as change in transition temperature by SYPRO orange dye based fluorescence-b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShiga toxin subunit A(Shigella dysenteriae)
TBA

Curated by ChEMBL
LigandPNGBDBM50199482(CHEMBL3963596)
Affinity DataIC50:  7.96E+3nMAssay Description:Inhibition of Shigella dysenteriae type 1 Shiga toxin A subunit in African green monkey Vero cells assessed as inhibition of Stx-induced cytotoxicity...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShiga toxin subunit A(Shigella dysenteriae)
TBA

Curated by ChEMBL
LigandPNGBDBM50199482(CHEMBL3963596)
Affinity DataKd:  716nMAssay Description:Binding affinity to recombinant Shigella dysenteriae type 1 Shiga toxin A subunit by SPR methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed