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Found 4 Enz. Inhib. hit(s) with Target = 'Sigma non-opioid intracellular receptor 1' and Ligand = 'BDBM50199790'
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
National Institute On Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50199790(CHEMBL3916231 | US10913711, Compound 9d | US115550...)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain cortex membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
National Institute On Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50199790(CHEMBL3916231 | US10913711, Compound 9d | US115550...)
Affinity DataKi:  4nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in whole-guinea pig brain minus cerebellum homogenates incubated for 120 mins by radioligand...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
The United States of America, As Represented By The Secretary, Department of Health and Human Services

US Patent
LigandPNGBDBM50199790(CHEMBL3916231 | US10913711, Compound 9d | US115550...)
Affinity DataKi:  4.03nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSigma non-opioid intracellular receptor 1(RAT)
The United States of America, As Represented By The Secretary, Department of Health and Human Services

US Patent
LigandPNGBDBM50199790(CHEMBL3916231 | US10913711, Compound 9d | US115550...)
Affinity DataKi:  4.03nMAssay Description:The uptake assays were carried out 2 days after transfection. Prior to the experiment, the cells were washed once in 500 ul of uptake buffer (25 mM 4...More data for this Ligand-Target Pair
In DepthDetails US Patent