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Found 3 Enz. Inhib. hit(s) with Target = 'Signal transducer and activator of transcription 3' and Ligand = 'BDBM50514302'
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50514302(CHEMBL4452527)
Affinity DataKi:  12nMAssay Description:Binding affinity to recombinant STAT3 (unknown origin) assessed as inhibition constant incubated for 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50514302(CHEMBL4452527)
Affinity DataKd:  44nMAssay Description:Binding affinity to His-SUMO-tagged human STAT3 (127 to 688 residues) expressed in Escherichia coli Rosette (DE3) assessed as dissociation constant u...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50514302(CHEMBL4452527)
Affinity DataKd:  44nMAssay Description:Binding affinity to recombinant human His/SUMO-tagged STAT3 (127 to 688 residues) expressed in Escherichia coli Rosetta (DE3) incubated for 1 hr by f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed