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Found
1
Enz. Inhib. hit(s) with Target = 'Sodium/hydrogen exchanger 3' and Ligand = 'BDBM381814'
Target
Sodium/hydrogen exchanger 3
(Homo sapiens (Human))
Ardelyx
US Patent
Ligand
BDBM381814
(US10272079, Compound 171)
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Affinity Data
IC50: 6.31nM
Assay Description:
Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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