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Found 2 Enz. Inhib. hit(s) with Target = 'Sodium/hydrogen exchanger 3' and Ligand = 'BDBM50601178'
TargetSodium/hydrogen exchanger 3(Homo sapiens (Human))
Ardelyx

Curated by ChEMBL
LigandPNGBDBM50601178(CHEMBL5202545)
Affinity DataIC50:  2nMAssay Description:Inhibition of human NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibito...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

Curated by ChEMBL
LigandPNGBDBM50601178(CHEMBL5202545)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of rat NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibitor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed