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Found 3 Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 1/2/3 subunit alpha' and Ligand = 'BDBM50017659'
TargetSodium channel protein type 1/2/3 subunit alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50017659(2-(Dimethylamino)ethyl p-(butylamino)benzoate | 2-...)
Affinity DataIC50:  400nMAssay Description:Antagonism of batrachotoxin-mediated sodium ion uptake into cultured neuroblastoma cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSodium channel protein type 1/2/3 subunit alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50017659(2-(Dimethylamino)ethyl p-(butylamino)benzoate | 2-...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50017659(2-(Dimethylamino)ethyl p-(butylamino)benzoate | 2-...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of [3H]batrachotoxin binding to rat brain neuronal membranesMore data for this Ligand-Target Pair
In DepthDetails Article