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Found 4 Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 1/2/3 subunit alpha' and Ligand = 'BDBM50366613'
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50366613(DEXTROMETHORPHAN)
Affinity DataKi:  4.80E+3nMAssay Description:Displacement of [3H]BTX from sodium channel of rat cerebral cortex synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50366613(DEXTROMETHORPHAN)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of [3H]batrachotoxin binding to rat brain sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50366613(DEXTROMETHORPHAN)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory effect against veratridine-induced glutamate release from rat brain slicesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50366613(DEXTROMETHORPHAN)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of [3H]saxitoxin binding to rat brain sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed