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Found 2 Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 1 subunit alpha' and Ligand = 'BDBM525940'
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM525940((S)-5-chloro-2-fluoro-4-((1-(2-fluorophenyl)propyl...)
Affinity DataIC50:  114nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM525940((S)-5-chloro-2-fluoro-4-((1-(2-fluorophenyl)propyl...)
Affinity DataIC50:  816nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent