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Found 2 Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 2 subunit alpha' and Ligand = 'BDBM50051088'
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50051088(CHEMBL3318147)
Affinity DataIC50:  8nMAssay Description:Inhibition of rat Nav1.7 expressed in HEK-293 cells at -130 to -110 mV holding potential by whole-cell voltage clamp analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50051088(CHEMBL3318147)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human Nav1.2 stably expressed in cells with train pulses to -20 mV at 0.1 Hz and holding potential of -95 mV by Qube-automated patch cl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed