Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 9 subunit alpha' and Ligand = 'BDBM50077465'
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50077465(CHEMBL3416892)
Affinity DataIC50:  27nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell patch clamp electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50077465(CHEMBL3416892)
Affinity DataIC50:  270nMAssay Description:Inhibition of human NaV1.7 at -140 mV holding potential by whole-cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50077465(CHEMBL3416892)
Affinity DataIC50:  270nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells assessed as inward peak current by ion-works quattro patch clamp electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed