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Found 3 Enz. Inhib. hit(s) with Target = 'Sodium- and chloride-dependent GABA transporter 2' and Ligand = 'BDBM50020883'
TargetSodium- and chloride-dependent GABA transporter 2(Rattus norvegicus)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50020883((R)-Piperidine-3-carboxylic acid | (R)-nipecotic a...)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibitory activity against rat GABA transporter-2 (rGAT2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 2(Mus musculus)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50020883((R)-Piperidine-3-carboxylic acid | (R)-nipecotic a...)
Affinity DataIC50:  8.70E+6nMAssay Description:Inhibition of [3H]GABA uptake at mouse GAT3 expressed in HEK293 cells after 3 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 2(Mus musculus)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50020883((R)-Piperidine-3-carboxylic acid | (R)-nipecotic a...)
Affinity DataIC50:  8.70E+6nMAssay Description:Inhibition of [3H]GABA uptake at mouse GAT3 expressed in HEK293 cells after 3 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed