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Found 2 Enz. Inhib. hit(s) with Target = 'Sodium- and chloride-dependent GABA transporter 2' and Ligand = 'BDBM50020891'
TargetSodium- and chloride-dependent GABA transporter 2(Mus musculus)
Ludwig-Maximilians-University Munich

Curated by ChEMBL
LigandPNGBDBM50020891((R)-1-(4,4-Diphenyl-but-3-enyl)-piperidine-3-carbo...)
Affinity DataIC50:  3.72E+5nMAssay Description:Inhibition of mouse GAT2 expressed in HEK cells assessed as inhibition of [3H]-GABA uptake after 25 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 2(Rattus norvegicus)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50020891((R)-1-(4,4-Diphenyl-but-3-enyl)-piperidine-3-carbo...)
Affinity DataIC50:  5.50E+5nMAssay Description:Inhibitory activity against rat GABA transporter-2 (rGAT2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed