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Found 2 Enz. Inhib. hit(s) with Target = 'Sodium- and chloride-dependent betaine transporter' and Ligand = 'BDBM50007525'
TargetSodium- and chloride-dependent betaine transporter(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50007525(CHEMBL123282 | N-(1-Benzyl-piperidin-4-yl)-2,3-dim...)
Affinity DataIC50:  9.10E+4nMAssay Description:Inhibition of human BGT1 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent betaine transporter(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50007525(CHEMBL123282 | N-(1-Benzyl-piperidin-4-yl)-2,3-dim...)
Affinity DataIC50:  9.12E+4nMAssay Description:Inhibition of human BGT1/human GAT3 chimera C expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed