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Found 4 Enz. Inhib. hit(s) with Target = 'Sodium-dependent dopamine transporter' and Ligand = 'BDBM22183'
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM22183(3-{4-[2-(diphenylmethoxy)ethyl]piperazin-1-yl}-1-p...)
Affinity DataKi:  208nMAssay Description:Binding affinity against dopamine transporter labelled with [125I]- RTI-55 in rat.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM22183(3-{4-[2-(diphenylmethoxy)ethyl]piperazin-1-yl}-1-p...)
Affinity DataKi:  208nMAssay Description:Binding affinity of the compound towards dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM22183(3-{4-[2-(diphenylmethoxy)ethyl]piperazin-1-yl}-1-p...)
Affinity DataKi:  210nM ΔG°:  -35.4kJ/molepH: 7.4 T: 2°CAssay Description:The assay was initiated by the addition of membranes to binding buffer containing test compound, blocker, and radioligand. The samples were incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM22183(3-{4-[2-(diphenylmethoxy)ethyl]piperazin-1-yl}-1-p...)
Affinity DataIC50:  329nMAssay Description:Reuptake inhibition of [3H]-labeled dopamine (DA) in rat.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed