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Found 3 Enz. Inhib. hit(s) with Target = 'Sodium-dependent dopamine transporter' and Ligand = 'BDBM30127'
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Human Biomolecular Research Institute

LigandPNGBDBM30127(CHEMBL480988 | phthalazinone, 20)
Affinity DataKi: >1.00E+5nM ΔG°: >-22.6kJ/mole EC50: >1.00E+5nMpH: 7.4 T: 2°CAssay Description:Binding affinity of each compound was measured by assessing the potency of inhibition of binding of radiolabeled RTI-55. Membranes were preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Human Biomolecular Research Institute

LigandPNGBDBM30127(CHEMBL480988 | phthalazinone, 20)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [125I]RTI55 from human recombinant DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Human Biomolecular Research Institute

LigandPNGBDBM30127(CHEMBL480988 | phthalazinone, 20)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of [3H]DA from human recombinant DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed