Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with Target = 'Sodium-dependent dopamine transporter' and Ligand = 'BDBM50069448'
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50069448((1R,2R)-3-Amino-2-naphthalen-2-yl-1-phenyl-propan-...)
Affinity DataKi:  6.20nMAssay Description:Inhibition of [3H]- DA reuptake into rat striatal synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Mayo Foundation

US Patent
LigandPNGBDBM50069448((1R,2R)-3-Amino-2-naphthalen-2-yl-1-phenyl-propan-...)
Affinity DataKi:  80.4nMAssay Description:DAT: This protocol was designed to measure inhibition of uptake by the human dopamine transporter. The reagents were human DAT (HEK293F) cells, GBR 1...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Mayo Foundation

US Patent
LigandPNGBDBM50069448((1R,2R)-3-Amino-2-naphthalen-2-yl-1-phenyl-propan-...)
Affinity DataKd:  140nMAssay Description:Equilibrium dissociation constant (KD) for Competitive binding between [3H]WIN-35428 and the compound at human transporter-hDATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed