Found 7 Enz. Inhib. hit(s) with Target = 'Sodium-dependent dopamine transporter' and Ligand = 'BDBM50199792' TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 114nMAssay Description:Displacement of [3H]WIN35,428 from Sprague-Dawley rat brain DAT after 120 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 116nMAssay Description:Displacement of [3H]WIN35,428 from DAT in Sprague-Dawley rat brain membranes incubated for 120 mins by radioligand binding assayMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 116nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quickly frozen. Membranes were prepared b...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 116nMAssay Description:Dopamine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quick...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 116nMAssay Description:Dopamine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quick...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataKi: 720nMAssay Description:Displacement of [3H]WIN35,428 from wild type human DAT expressed in COS7 cell membranes incubated for >90 mins by radioligand binding assayMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataKi: 890nMAssay Description:Inhibition of DAT (unknown origin) expressed in COS7 cells assessed as reduction in [3H]DA uptake incubated for 5 mins by beta-scintillation counting...More data for this Ligand-Target Pair
