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Found 4 Enz. Inhib. hit(s) with Target = 'Sodium-dependent dopamine transporter' and Ligand = 'BDBM50336892'
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50336892((R)-Modafinil | ARMODAFINIL | CHEMBL1201192 | Nuvi...)
Affinity DataKi:  647nMAssay Description:Displacement of [3H]WIN35,428 from wild type human DAT expressed in COS7 cell membranes incubated for >90 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50336892((R)-Modafinil | ARMODAFINIL | CHEMBL1201192 | Nuvi...)
Affinity DataKi:  3.05E+3nMAssay Description:Displacement of [3H]WIN35,428 from DAT in Sprague-Dawley rat brain membranes incubated for 120 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50336892((R)-Modafinil | ARMODAFINIL | CHEMBL1201192 | Nuvi...)
Affinity DataKi:  3.26E+3nMAssay Description:Displacement of [3H]WIN35428 from DAT in Sprague-Dawley rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50336892((R)-Modafinil | ARMODAFINIL | CHEMBL1201192 | Nuvi...)
Affinity DataIC50:  6.60E+3nMAssay Description:Inhibition of wild type human dopamine transporter expressed in HEK293 cells assessed as inhibition of [3H]dopamine reuptake preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed