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Found 3 Enz. Inhib. hit(s) with Target = 'Sodium-dependent noradrenaline transporter' and Ligand = 'BDBM388642'
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Mayo Foundation

US Patent
LigandPNGBDBM388642(Reboxe- tine | US9944618, Compound ID No. 178)
Affinity DataKi:  2.90nMAssay Description:NET: This protocol was designed to measure inhibition of uptake by the human norepinephrine transporter. The reagents were human NET (HEK293F) cells,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Mayo Foundation

US Patent
LigandPNGBDBM388642(Reboxe- tine | US9944618, Compound ID No. 178)
Affinity DataKi:  39nMAssay Description:Displacement of [3H]-nisoxetine from human NET expressed in HEK293 cell membranes incubated for 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Mayo Foundation

US Patent
LigandPNGBDBM388642(Reboxe- tine | US9944618, Compound ID No. 178)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of human NET expressed in HEK293 cells assessed as reduction in ASP+ uptake incubated for 20 mins before ASP+ addition and measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed