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Found 4 Enz. Inhib. hit(s) with Target = 'Sodium-dependent noradrenaline transporter' and Ligand = 'BDBM50132686'
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50132686(CHEMBL326466 | Dimethyl-((2S,3S)-3-naphthalen-2-yl...)
Affinity DataKi:  152nMAssay Description:Displacement of [3H]-Nisoxetine from norepinephrin transpoterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50132686(CHEMBL326466 | Dimethyl-((2S,3S)-3-naphthalen-2-yl...)
Affinity DataIC50:  25nMAssay Description:In vitro inhibition of [3H]-NE re-uptake into synaptosomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50132686(CHEMBL326466 | Dimethyl-((2S,3S)-3-naphthalen-2-yl...)
Affinity DataIC50:  25nMAssay Description:Inhibition of NET (unknown origin) assessed as reduction of [3H]-NE re-uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50132686(CHEMBL326466 | Dimethyl-((2S,3S)-3-naphthalen-2-yl...)
Affinity DataIC50:  25nMAssay Description:Inhibition constant against norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed