Found 12 Enz. Inhib. hit(s) with Target = 'Sodium-dependent serotonin transporter' and Ligand = 'BDBM50124566'
Affinity DataKi: 60nMAssay Description:Invitro competitive binding versus [N-methyl-3H]-WIN 35428 in murine kidney cells transfected with cDNA for human dopamine transporter (DAT)More data for this Ligand-Target Pair
Affinity DataKi: 129nMAssay Description:Inhibition of [125I]-RTI-55 binding to human serotonin transporter expressed in human embryonic kidney cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wayne State University
Curated by ChEMBL
Wayne State University
Curated by ChEMBL
Affinity DataKi: 503nMAssay Description:Inhibition of SERT in rat cerebral cortex assessed as [3H]serotonin accumulationMore data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nMAssay Description:Inhibition of [3H]Citalopram uptake in human 5HTT transfected HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 242nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 242nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in JAR celsMore data for this Ligand-Target Pair
Affinity DataIC50: 242nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in JAR cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 242nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wayne State University
Curated by ChEMBL
Wayne State University
Curated by ChEMBL
Affinity DataIC50: >500nMAssay Description:Binding affinity against serotonin transporter (SERT) by displacement of [3H]paroxetine in male wistar ratsMore data for this Ligand-Target Pair
Affinity DataIC50: 590nMAssay Description:Inhibition of [3H]5-HT reuptake at 5HT transporter in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 590nMAssay Description:Inhibition of [3H]5-HT uptake at 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair